Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.41 |
| ▸ | CNR1 | P21554 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834777 | 0.85 | CNR2 (0.40) | CNR2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL28834819 | 0.77 | ALDH1A1 (0.44) | CNR2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL28569112 | 0.75 | CNR2 (0.59) | CNR2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL23590651 | 0.71 | ALDH1A1 (0.46) | KDM4EALDH1A1CYP2C19CYP3A4HSD17B10 | |
| SCHEMBL30035755 | 0.71 | ALDH1A1 (0.46) | KDM4EALDH1A1CYP2C19CYP3A4HSD17B10 | |
| SCHEMBL30183967 | 0.71 | ALDH1A1 (0.46) | KDM4EALDH1A1CYP2C19CYP3A4HSD17B10 | |
| SCHEMBL15997879 | 0.70 | CNR2 (0.56) | CNR2CNR1 | |
| SCHEMBL12584413 | 0.70 | CNR2 (0.48) | CNR2CNR1 | |
| SCHEMBL21231982 | 0.70 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL20727113 | 0.69 | PTGER4 (0.40) | CNR2CNR1LMNAPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028644-A | SOS1 inhibitor heterocyclic compounds | 首药控股(北京)股份有限公司 | 2022-09-09 | — | — | CN | disclosed |