Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.59 |
| ▸ | CNR1 | P21554 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28563850 | 0.88 | ALDH1A1 (0.59) | CNR2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL28586562 | 0.85 | CNR2 (0.46) | CNR2CNR1EPHX2PPARG | |
| SCHEMBL5452646 | 0.80 | ALDH1A1 (0.70) | CNR2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL20436343 | 0.77 | HTR2A (0.48) | CNR2CNR1CYP2C9CYP2C19 | |
| SCHEMBL2324058 | 0.77 | TUBB4A (0.62) | KDM4EALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL13699049 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL3144113 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL31200152 | 0.75 | MAPT (0.43) | KDM4EALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL28834838 | 0.75 | CNR2 (0.41) | CNR2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL23902660 | 0.75 | CNR2 (0.49) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759541-B | Indole-like derivatives and uses thereof | 复旦大学 | 2023-03-17 | — | — | CN | disclosed |
| CN-112759541-A | Indole-like derivatives and uses thereof | 复旦大学 | 2021-05-07 | — | — | CN | disclosed |