Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | CFTR | P13569 | 3/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834792 | 0.83 | SIRT6 (0.42) | ALDH1A1GAAMAPTHPGDLMNA | |
| SCHEMBL27186173 | 0.78 | ALDH1A1 (0.45) | ALDH1A1KDM4ECFTRGAAHSD17B10 | |
| SCHEMBL28834838 | 0.77 | CNR2 (0.41) | ALDH1A1KDM4ECFTRGAAHSD17B10 | |
| SCHEMBL29901725 | 0.77 | KDM4E (0.39) | ALDH1A1KDM4ECFTRGAAHSD17B10 | |
| SCHEMBL15998985 | 0.75 | HTR3A (0.43) | ALDH1A1MAPTOPRK1CNR1CNR2 | |
| SCHEMBL31438003 | 0.75 | FGFR1 (0.43) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL21231982 | 0.74 | KDM4E (0.49) | ALDH1A1KDM4ECFTRGAAHSD17B10 | |
| SCHEMBL20606472 | 0.74 | IRAK4 (0.58) | ALDH1A1KDM4EIRAK4 | |
| SCHEMBL23530107 | 0.71 | KDM4C (0.37) | ALDH1A1KDM4EDGAT1KDM4CIRAK4 | |
| SCHEMBL29550517 | 0.71 | KDM4C (0.37) | ALDH1A1KDM4EDGAT1KDM4CIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028644-A | SOS1 inhibitor heterocyclic compounds | 首药控股(北京)股份有限公司 | 2022-09-09 | — | — | CN | disclosed |