Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.53 |
| ▸ | RAPGEF4 | Q8WZA2 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | FGB | P02675 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15386170 | 0.74 | CYP1A2 (0.37) | MAPTNPSR1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7002330 | 0.71 | CA1 (0.37) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL17922970 | 0.71 | ALDH1A1 (0.35) | PIK3CAMAPTHTTTDP1ALDH1A1 | |
| SCHEMBL17960655 | 0.68 | HTT (0.69) | RAPGEF4MAPTNPSR1HTTTDP1 | |
| SCHEMBL15188829 | 0.67 | RAPGEF4 (1.00) | RAPGEF4MAPTNPSR1HTTTDP1 | |
| SCHEMBL12137521 | 0.67 | OGG1 (0.58) | PIK3CDPIK3CAPIK3CBPIK3CGRAPGEF4 | |
| SCHEMBL17960742 | 0.65 | RAPGEF4 (0.47) | RAPGEF4MAPTNPSR1HTTTDP1 | |
| SCHEMBL28748648 | 0.65 | ESR2 (0.46) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL27547737 | 0.64 | CYP1A2 (0.38) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL5694221 | 0.64 | RAPGEF4 (0.45) | PIK3CDPIK3CAPIK3CBPIK3CGRAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146401-A | A kind of indazole derivative and combinations thereof thing and purposes | 北京赛林泰医药技术有限公司 | 2016-11-23 | — | — | CN | disclosed |