1-Hydroxy-3-Methoxybenzene

1-Hydroxy-3-Methoxybenzene

SCHEMBL28835526

C=CC(=O)O.COc1cccc(O)c1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.58
ESR2 Q92731 1/20 0.58
CYP3A4 P08684 1/20 0.51
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
MAPT P10636 1/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
MMP1 P03956 1/20 0.49
MMP2 P08253 1/20 0.49
MMP9 P14780 1/20 0.49
CES2 O00748 1/20 0.49
CES1 P23141 1/20 0.49
LMNA P02545 1/20 0.47
ABL1 P00519 1/20 0.47
BCR P11274 1/20 0.47
NR1H4 Q96RI1 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anisole SCHEMBL28850433 0.86 CA4 (0.52) ESR2CYP3A4MEN1KMT2ANPC1
1-Hydroxy-3-Methoxybenzene SCHEMBL10922424 0.85 ESR1 (0.56) ESR1ESR2CYP3A4MEN1KMT2A
1-Hydroxy-3-Methoxybenzene SCHEMBL27611510 0.85 ESR1 (0.64) ESR1ESR2CYP3A4MEN1KMT2A
1-Hydroxy-3-Methoxybenzene SCHEMBL28214358 0.83 ESR1 (0.67) ESR1ESR2CYP3A4MEN1KMT2A
1-Hydroxy-3-Methoxybenzene SCHEMBL28256 0.83
1-Hydroxy-3-Methoxybenzene SCHEMBL29421717 0.83
Acrylic Acid SCHEMBL9765760 0.83 ACHE (0.66) MEN1KMT2ANPC1RAB9AMAPT
1-Hydroxy-3-Methoxybenzene SCHEMBL5778012 0.82 ESR1 (0.60) ESR1ESR2CYP3A4MEN1KMT2A
1-Hydroxy-3-Methoxybenzene SCHEMBL27470118 0.82 ESR1 (0.60) ESR1ESR2CYP3A4MEN1KMT2A
Acrylic Acid SCHEMBL28304089 0.81 CES2 (0.51) MEN1KMT2ANPC1RAB9ACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105998040-A Preparation method of medicine for treating cardiovascular disease 胡小丽 2016-10-12 CN claimed