SCHEMBL28835527

SCHEMBL28835527

C1CC2CCNCNCCNCC(C1)N2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5832222 0.91 HTR3A (0.30)
SCHEMBL8192003 0.84 SMN1; SMN2 (0.35)
SCHEMBL28882571 0.84 SMN1; SMN2 (0.35)
SCHEMBL24254052 0.81
SCHEMBL503209 0.81
SCHEMBL16878573 0.77 SLC6A1 (0.38)
SCHEMBL702038 0.75
SCHEMBL23505391 0.75
SCHEMBL16878175 0.71
SCHEMBL1449497 0.70 CCR5 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114984255-A Radionuclide-labeled PSMA-alpha v beta 3 double-target couplet and application thereof 苏州大学 2022-09-02 CN disclosed