Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15709188 | 0.82 | TGM2 (0.73) | TGM2SMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL15709186 | 0.82 | TGM2 (0.73) | TGM2SMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL6481014 | 0.80 | TGM2 (0.71) | TGM2SMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL28108366 | 0.79 | TGM2 (0.59) | TGM2SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL2098409 | 0.79 | TGM2 (0.69) | TGM2SMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL782552 | 0.79 | TGM2 (1.00) | TGM2SMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL1416227 | 0.78 | TGM2 (0.57) | TGM2SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL3698398 | 0.78 | TGM2 (0.62) | TGM2SMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL9943778 | 0.78 | CNR1 (0.80) | TGM2SMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL17152538 | 0.77 | TGM2 (0.54) | TGM2SMN1; SMN2NPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132940-A | New kallikrein 7 inhibitor | 西可斯拉制药公司 | 2016-11-16 | — | — | CN | claimed |
| CN-106132940-A | New kallikrein 7 inhibitor | 西可斯拉制药公司 | 2016-11-16 | — | — | CN | disclosed |