Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MMP1 | P03956 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1416227 | 0.81 | TGM2 (0.57) | TGM2MEN1KMT2AMAPTMMP1 | |
| SCHEMBL28835697 | 0.79 | TGM2 (0.65) | TGM2MEN1KMT2AMAPTMMP1 | |
| SCHEMBL17152485 | 0.76 | TGM2 (0.49) | TGM2MEN1KMT2AMAPTMMP1 | |
| SCHEMBL29246294 | 0.76 | TGM2 (0.61) | TGM2MEN1KMT2AMAPTMMP1 | |
| SCHEMBL5645657 | 0.76 | SMN1; SMN2 (0.68) | TGM2MEN1KMT2AMAPTMMP1 | |
| SCHEMBL9301283 | 0.75 | TGM2 (0.56) | TGM2MEN1KMT2AMAPTMMP1 | |
| SCHEMBL4790863 | 0.75 | ALDH1A1 (0.65) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL1383591 | 0.75 | TGM2 (1.00) | TGM2MEN1KMT2AMMP1MMP2 | |
| SCHEMBL13113092 | 0.74 | TGM2 (0.59) | TGM2MEN1KMT2AMAPTMMP1 | |
| Fluoride SCHEMBL27918634 | 0.73 | ALDH1A1 (0.62) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132940-B | New kallikrein 7 inhibitor | 西可斯拉制药公司 | 2019-04-23 | — | — | CN | claimed |
| CN-106132940-A | New kallikrein 7 inhibitor | 西可斯拉制药公司 | 2016-11-16 | — | — | CN | claimed |
| CN-106132940-B | New kallikrein 7 inhibitor | 西可斯拉制药公司 | 2019-04-23 | — | — | CN | disclosed |
| CN-106132940-A | New kallikrein 7 inhibitor | 西可斯拉制药公司 | 2016-11-16 | — | — | CN | disclosed |