Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28835850 | 0.87 | RXRA (0.54) | ERN1EGFRRXRAKDM4ELMNA | |
| SCHEMBL14060389 | 0.83 | KDM4E (0.53) | CA1CA2CA12CA9CA14 | |
| SCHEMBL4652494 | 0.81 | ERN1 (0.64) | ERN1EGFRPTPN1CA1CA2 | |
| SCHEMBL28835962 | 0.81 | NOTUM (0.46) | ERN1EGFRCA1CA2CA12 | |
| SCHEMBL10009170 | 0.80 | CA1 (0.61) | ERN1EGFRPTPN1CA1CA2 | |
| SCHEMBL16749645 | 0.80 | CA1 (0.61) | ERN1EGFRPTPN1CA1CA2 | |
| SCHEMBL20388646 | 0.79 | ERN1 (0.70) | ERN1EGFRPTPN1CA1CA2 | |
| SCHEMBL204640 | 0.79 | TSHR (0.61) | EGFRPTPN1CA1CA2CA12 | |
| SCHEMBL19387238 | 0.78 | CA1 (0.70) | ERN1EGFRPTPN1CA1CA2 | |
| Biphenyl Dimethyl Dicarboxylate SCHEMBL68521 | 0.78 | CA1 (0.70) | ERN1EGFRPTPN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010600-B | Method for synthesizing polyfluoroaryl carboxylic acid compound based on aryl fluorocarbon bond carboxylation reaction | 四川大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-115010600-A | Method for synthesizing polyfluoroaryl carboxylic acid compounds based on aryl fluorocarbon bond carboxylation reaction | 四川大学 | 2022-09-06 | — | — | CN | disclosed |