Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | IL2 | P60568 | 3/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28835961 | 0.89 | LMNA (0.44) | NOTUMSLC2A1ROCK2ROCK1EGFR | |
| SCHEMBL28835849 | 0.81 | ERN1 (0.59) | EGFRERN1CA12CA1CA2 | |
| SCHEMBL7402540 | 0.81 | SLC2A1 (0.56) | NOTUMSLC2A1ROCK2ROCK1EGFR | |
| SCHEMBL3748237 | 0.79 | EGFR (0.63) | SLC2A1ROCK2ROCK1EGFRCA12 | |
| SCHEMBL28268790 | 0.79 | KDM4E (0.54) | NOTUMSLC2A1EGFRCA12CA1 | |
| SCHEMBL28255681 | 0.79 | SLC2A1 (0.63) | SLC2A1ROCK2ROCK1EGFRERN1 | |
| SCHEMBL16937873 | 0.78 | TDP1 (0.57) | NOTUMSLC2A1EGFRCA12CA1 | |
| SCHEMBL28905197 | 0.78 | SLC2A1 (0.59) | SLC2A1EGFRCA12CA1CA2 | |
| SCHEMBL2769544 | 0.77 | HSD17B1 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15921270 | 0.77 | MAPT (0.53) | NOTUMSLC2A1ROCK2ROCK1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010600-B | Method for synthesizing polyfluoroaryl carboxylic acid compound based on aryl fluorocarbon bond carboxylation reaction | 四川大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-115010600-A | Method for synthesizing polyfluoroaryl carboxylic acid compounds based on aryl fluorocarbon bond carboxylation reaction | 四川大学 | 2022-09-06 | — | — | CN | disclosed |