Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 18/20 | 0.69 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.69 |
| ▸ | MMP2 | P08253 | 1/20 | 0.69 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.69 |
| ▸ | AKR1C2 | P52895 | 10/20 | 0.59 |
| ▸ | AKR1C4 | P17516 | 5/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6706138 | 0.83 | AKR1C3 (0.61) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL6706139 | 0.83 | AKR1C3 (0.61) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL1229229 | 0.81 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL2138507 | 0.81 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL7128580 | 0.81 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL3684666 | 0.80 | AKR1C3 (0.80) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL3684668 | 0.80 | AKR1C3 (0.80) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL8746675 | 0.78 | HCAR2 (0.64) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL8746677 | 0.78 | HCAR2 (0.64) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL8467358 | 0.78 | AKR1C3 (0.86) | AKR1C3AKR1B10AKR1B1MMP2PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106242987-B | A kind of prevention and treatment diabetes and medicine for treating diabetic nephropathy and its synthetic method and application | 西安科技大学 | 2019-02-22 | — | — | CN | disclosed |
| CN-106349099-B | Caffeic acid-lysine and its derivative, preparation method and purposes | 西安科技大学 | 2018-08-07 | — | — | CN | disclosed |
| CN-106349099-A | Caffeic acid-lysine and derivatives, preparation method and application thereof | 西安科技大学 | 2017-01-25 | — | — | CN | disclosed |
| CN-106242987-A | One prevents and treats diabetes and medicine for treating diabetic nephropathy and synthetic method thereof and application | 西安科技大学 | 2016-12-21 | — | — | CN | disclosed |