Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29714417 | 1.00 | KMT2A (0.47) | KMT2ATSHRMEN1ALDH1A1POLB | |
| SCHEMBL28836744 | 0.89 | TSHR (0.48) | KMT2ATSHRMEN1ALDH1A1POLB | |
| SCHEMBL29714457 | 0.89 | TSHR (0.48) | KMT2ATSHRMEN1ALDH1A1POLB | |
| SCHEMBL29714456 | 0.77 | TSHR (0.50) | KMT2ATSHRMEN1ALDH1A1POLB | |
| SCHEMBL28952600 | 0.77 | TSHR (0.50) | KMT2ATSHRMEN1ALDH1A1POLB | |
| SCHEMBL30688097 | 0.77 | LMNA (0.52) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL29101145 | 0.77 | LMNA (0.52) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL28836713 | 0.76 | MEN1 (0.38) | KMT2ATSHRMEN1ALDH1A1LMNA | |
| SCHEMBL29101134 | 0.69 | KCNN4 (0.56) | LMNACTSGGAA | |
| SCHEMBL30688098 | 0.69 | KCNN4 (0.56) | LMNACTSGGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716374-A | 3-substituted dihydroquinoline derivative and preparation method thereof | 武汉工程大学 | 2022-07-08 | — | — | CN | disclosed |