Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30688097 | 1.00 | LMNA (0.52) | LMNATHRBMEN1KMT2AKCNN4 | |
| SCHEMBL29101134 | 0.94 | KCNN4 (0.56) | LMNATHRBKCNN4KCNA3MMP2 | |
| SCHEMBL30688098 | 0.94 | KCNN4 (0.56) | LMNATHRBKCNN4KCNA3MMP2 | |
| SCHEMBL28836746 | 0.90 | KCNN4 (0.54) | LMNAKCNN4KCNA3MMP2TP53 | |
| SCHEMBL29714451 | 0.90 | KCNN4 (0.54) | LMNAKCNN4KCNA3MMP2TP53 | |
| SCHEMBL29714455 | 0.87 | KCNN4 (0.44) | LMNATHRBMEN1KMT2AKCNN4 | |
| SCHEMBL29101141 | 0.87 | KCNN4 (0.44) | LMNATHRBMEN1KMT2AKCNN4 | |
| SCHEMBL28836780 | 0.85 | KCNN4 (0.50) | LMNAMEN1KMT2AKCNN4KCNA3 | |
| SCHEMBL28836713 | 0.84 | MEN1 (0.38) | LMNATHRBMEN1KMT2AKCNN4 | |
| SCHEMBL29101146 | 0.82 | KCNN4 (0.47) | KCNN4KCNA3MMP2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716374-B | 3-bit substituted dihydroquinoline derivative and preparation method thereof | 武汉工程大学 | 2023-11-07 | — | — | CN | disclosed |