Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836742 | 0.91 | HSD17B10 (0.44) | MEN1KMT2ALMNAHSD17B10CTSG | |
| SCHEMBL30688097 | 0.84 | LMNA (0.52) | MEN1KMT2ALMNATHRBALDH1A1 | |
| SCHEMBL29101145 | 0.84 | LMNA (0.52) | MEN1KMT2ALMNATHRBALDH1A1 | |
| SCHEMBL28952599 | 0.79 | HSD17B10 (0.43) | MEN1KMT2ALMNAHSD17B10CTSG | |
| SCHEMBL29101134 | 0.77 | KCNN4 (0.56) | LMNATHRBCTSGCMA1PKM | |
| SCHEMBL30688098 | 0.77 | KCNN4 (0.56) | LMNATHRBCTSGCMA1PKM | |
| SCHEMBL28836714 | 0.76 | KMT2A (0.47) | MEN1KMT2ALMNACTSGMAPK1 | |
| SCHEMBL29714417 | 0.76 | KMT2A (0.47) | MEN1KMT2ALMNACTSGMAPK1 | |
| SCHEMBL28836746 | 0.73 | KCNN4 (0.54) | LMNACTSGCMA1ALDH1A1KCNN4 | |
| SCHEMBL29714451 | 0.73 | KCNN4 (0.54) | LMNACTSGCMA1ALDH1A1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716374-A | 3-substituted dihydroquinoline derivative and preparation method thereof | 武汉工程大学 | 2022-07-08 | — | — | CN | disclosed |