Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483229 | 0.82 | FOLH1 (0.74) | FOLH1ENPEPLMNASLC22A6TSHR | |
| SCHEMBL25380649 | 0.81 | CAMK2A (0.46) | FOLH1ENPEPCA1CA2LMNA | |
| SCHEMBL27562533 | 0.81 | CA2 (0.67) | CA1CA2 | |
| SCHEMBL10479750 | 0.79 | CA2 (0.59) | CA1CA2 | |
| SCHEMBL8416810 | 0.78 | FOLH1 (0.50) | FOLH1ENPEPLMNASLC22A6TSHR | |
| SCHEMBL9157043 | 0.78 | FOLH1 (0.46) | FOLH1CA1CA2LMNASLC22A6 | |
| SCHEMBL9860566 | 0.78 | GPR84 (0.58) | CA1CA2 | |
| SCHEMBL7865182 | 0.78 | GPR84 (0.58) | CA1CA2 | |
| SCHEMBL31241195 | 0.78 | GPR84 (0.58) | CA1CA2 | |
| Hydrochloric Acid SCHEMBL3290017 | 0.78 | CPB2 (0.52) | FOLH1CA1CA2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106190997-A | A kind of dependent diaminopimelate dehydrogenase of NADH and application thereof | 清华大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106190997-A | A kind of dependent diaminopimelate dehydrogenase of NADH and application thereof | 清华大学 | 2016-12-07 | — | — | CN | disclosed |