SCHEMBL1069101

SCHEMBL1069101

O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(O)nc(O)nc32)C[C@@H]1O

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.56
▸ NT5E P21589 1/20 0.54
▸ P2RY6 Q15077 3/20 0.53
▸ P2RY2 P41231 2/20 0.53
▸ P2RY4 P51582 2/20 0.53
▸ ENPP1 P22413 5/20 0.50
▸ P2RY1 P47900 4/20 0.50
▸ P2RX3 P56373 3/20 0.49
▸ P2RX2 Q9UBL9 2/20 0.49
▸ P2RX1 P51575 2/20 0.49
▸ P2RY11 Q96G91 1/20 0.49
▸ P2RX4 Q99571 1/20 0.49
▸ P2RY12 Q9H244 1/20 0.47
▸ DTYMK P23919 2/20 0.47
▸ RNASEL Q05823 1/20 0.46
▸ GPR17 Q13304 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19180617 0.99 POLB (0.57) POLBNT5EP2RY6P2RY2P2RY4
SCHEMBL2883759 0.91 NT5E (0.58) POLBNT5EENPP1P2RY1
SCHEMBL29642033 0.91 NT5E (0.64) POLBNT5EP2RY6P2RY2P2RY4
SCHEMBL15573313 0.91 NT5E (0.64) POLBNT5EP2RY6P2RY2P2RY4
SCHEMBL29465233 0.89 POLB (0.65) POLBP2RY2ENPP1P2RY1P2RX3
SCHEMBL1763078 0.89 POLB (0.65) POLBP2RY2ENPP1P2RY1P2RX3
SCHEMBL245486 0.89 POLB (0.65) POLBP2RY2ENPP1P2RY1P2RX3
SCHEMBL2508646 0.87 POLB (0.66) POLBNT5EP2RY2ENPP1P2RY1
SCHEMBL2508660 0.87 POLB (0.66) POLBNT5EP2RY2ENPP1P2RY1
Triphosphate SCHEMBL28101757 0.87 POLB (0.61) POLBNT5EP2RY6P2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140170689-A1 Modified Diguanylate Cyclase-Phosphodiesterase and Method for Enzymatic Production of Cyclic-diGMP THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2014-06-19 — — US claimed
JP-2011505845-A — — 2011-03-03 — — JP claimed
US-20110003700-A1 ELIMINATION OF CONTAMINANTS ASSOCIATED WITH NUCLEIC ACID AMPLIFICATION HUMAN GENETIC SIGNATURES PTY LTD. (AU) 2011-01-06 — — US claimed
EP-2222850-A1 ELIMINATION OF CONTAMINANTS ASSOCIATED WITH NUCLEIC ACID AMPLIFICATION Human Genetic Signatures Pty Ltd (AU) 2010-09-01 — — EP claimed
WO-2009079703-A1 ELIMINATION OF CONTAMINANTS ASSOCIATED WITH NUCLEIC ACID AMPLIFICATION HUMAN GENETIC SIGNATURES PTY LTD (AU) 2009-07-02 — — WO claimed
EP-1595957-A1 Phosphoglycerate mutases and enzyme products Eigenbrodt, Erich (DE) 2005-11-16 — — EP claimed
CN-122055456-A Gene recognition profile for liver disease and uses thereof 新加坡科技研究局 2026-05-15 — — CN disclosed
EP-4729632-A1 METHOD OF SYNTHESIZING DNA AskBio Inc. (US) 2026-04-22 — — EP disclosed
US-20260028659-A1 SYNTHESIS OF DNA WITH IMPROVED YIELD Touchlight IP Limited (GB) 2026-01-29 — — US disclosed
EP-4665865-A1 METHODS OF MAKING DNA MOLECULES AND COMPOSITIONS AND USES THEREOF Anjarium Biosciences AG (CH) 2025-12-24 — — EP disclosed
WO-2025151077-A1 A METHOD TO PREDICT AND TARGET RESISTANCE TO CHEMOTHERAPY IN A CANCER NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-07-17 — — WO disclosed
WO-2025133639-A1 DUPLEXING METHOD Touchlight IP Limited (GB) 2025-06-26 — — WO disclosed
US-20250136636-A1 NUCLEOTIDE COMPLEXES CAPABLE OF AN IMPROVED DNA SYNTHESIS YIELD Touchlight IP Limited (GB) 2025-05-01 — — US disclosed
US-7947477-B2 Emulsion PCR and amplicon capture APPLIED BIOSYSTEMS, LLC (US) 2011-05-24 — — US disclosed
US-20110003700-A1 ELIMINATION OF CONTAMINANTS ASSOCIATED WITH NUCLEIC ACID AMPLIFICATION HUMAN GENETIC SIGNATURES PTY LTD. (AU) 2011-01-06 — — US disclosed
EP-2222850-A1 ELIMINATION OF CONTAMINANTS ASSOCIATED WITH NUCLEIC ACID AMPLIFICATION Human Genetic Signatures Pty Ltd (AU) 2010-09-01 — — EP disclosed
US-20100129875-A1 EMULSION PCR AND AMPLICON CAPTURE Life Technologies Corporation (US) 2010-05-27 — — US disclosed
WO-2009079703-A1 ELIMINATION OF CONTAMINANTS ASSOCIATED WITH NUCLEIC ACID AMPLIFICATION HUMAN GENETIC SIGNATURES PTY LTD (AU) 2009-07-02 — — WO disclosed
US-20080076909-A1 EMULSION PCR AND AMPLICON CAPTURE APPLERA CORPORATION (US) 2008-03-27 — — US disclosed
WO-2008005675-A2 EMULSION PCR AND AMPLICON CAPTURE APPLERA CORPORATION (US) 2008-01-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028659-A1 SYNTHESIS OF DNA WITH IMPROVED YIELD POLB, DNMT3A, POLM POLB 1/4885NT5E 163/4885P2RY6 2113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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