Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.46 |
| ▸ | DDX3X | O00571 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718873 | 0.84 | MEN1 (0.58) | POLBMEN1KMT2AAKR1C3RIPK1 | |
| SCHEMBL30417005 | 0.83 | RIPK1 (0.55) | POLBMEN1KMT2AAKR1C3RIPK1 | |
| SCHEMBL29014398 | 0.83 | RIPK1 (0.55) | POLBMEN1KMT2AAKR1C3RIPK1 | |
| SCHEMBL1333872 | 0.81 | MEN1 (0.51) | MEN1KMT2AAKR1C3RIPK1CSNK1A1 | |
| SCHEMBL1663100 | 0.81 | MEN1 (0.68) | MEN1KMT2AAKR1C3RIPK1CSNK1A1 | |
| SCHEMBL1163897 | 0.81 | MEN1 (0.71) | POLBMEN1KMT2AAKR1C3CSNK1D | |
| SCHEMBL1999901 | 0.80 | AKR1C3 (0.63) | MEN1KMT2AAKR1C3DDX3XNPC1 | |
| SCHEMBL239690 | 0.80 | MEN1 (0.75) | POLBMEN1KMT2AAKR1C3RIPK1 | |
| SCHEMBL30020996 | 0.80 | MEN1 (0.75) | POLBMEN1KMT2AAKR1C3RIPK1 | |
| SCHEMBL30289874 | 0.80 | MAPT (0.58) | POLBMEN1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890952-B | Preparation method of 5-halogeno-2-aminobenzoazacyclic compound | 重庆医科大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-114890952-A | Preparation method of 5-halogenated-2-aminobenzene nitrogen heterocyclic compound | 重庆医科大学 | 2022-08-12 | — | — | CN | disclosed |