Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.55 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | DDX3X | O00571 | 1/20 | 0.43 |
| ▸ | RHEB | Q15382 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29014398 | 1.00 | RIPK1 (0.55) | RIPK1CSNK1A1CSNK1DGSK3BCSNK1G2 | |
| SCHEMBL28837680 | 0.83 | POLB (0.56) | RIPK1CSNK1A1CSNK1DGSK3BCSNK1G2 | |
| SCHEMBL5365311 | 0.81 | KDM4E (0.52) | CSNK1A1CSNK1DGSK3BCSNK1G2POLB | |
| SCHEMBL30822891 | 0.81 | HDAC11 (0.62) | RIPK1CSNK1A1CSNK1DGSK3BCSNK1G2 | |
| SCHEMBL9718873 | 0.79 | MEN1 (0.58) | RIPK1CSNK1A1CSNK1DGSK3BCSNK1G2 | |
| SCHEMBL9718864 | 0.79 | RIPK1 (0.63) | RIPK1CSNK1A1CSNK1DGSK3BCSNK1G2 | |
| SCHEMBL5361414 | 0.78 | KDR (0.49) | CSNK1A1CSNK1DGSK3BCSNK1G2POLB | |
| SCHEMBL4164559 | 0.78 | KDR (0.63) | CSNK1A1CSNK1DGSK3BCSNK1G2POLB | |
| SCHEMBL20096459 | 0.78 | HDAC11 (0.78) | POLBMEN1KMT2AHDAC11AKR1C3 | |
| SCHEMBL29624674 | 0.78 | HDAC11 (0.78) | POLBMEN1KMT2AHDAC11AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890952-B | Preparation method of 5-halogeno-2-aminobenzoazacyclic compound | 重庆医科大学 | 2023-06-06 | — | — | CN | disclosed |