Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2883716 | 0.85 | ESR1 (0.59) | GABRA1GABRB2ESR1ESR2MEN1 | |
| SCHEMBL29632697 | 0.84 | KDM4E (0.46) | GABRA1GABRB2ESR1ESR2MEN1 | |
| SCHEMBL900106 | 0.83 | ESR1 (0.51) | GABRA1GABRB2ESR1ESR2MEN1 | |
| SCHEMBL10051848 | 0.80 | ESR1 (0.47) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL2883963 | 0.79 | ESR1 (0.47) | GABRA1GABRB2ESR1ESR2MEN1 | |
| SCHEMBL30366138 | 0.79 | PDK2 (0.39) | GABRA1GABRB2ESR1ESR2MEN1 | |
| SCHEMBL383342 | 0.79 | PDK2 (0.39) | GABRA1GABRB2ESR1ESR2MEN1 | |
| SCHEMBL10076748 | 0.78 | ESR1 (0.50) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL2886031 | 0.77 | ESR1 (0.45) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL2883801 | 0.76 | BCL2 (0.46) | ESR1ESR2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781540-B2 | Resin composition and molded articles thereof | OSAKA GAS CO., LTD. (JP) | 2010-08-24 | — | — | US | disclosed |
| US-7772356-B2 | Infrared absorption filter | OSAKA GAS CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-7645534-B2 | Membrane electrode assembly for solid polymer electrolyte fuel cell | HONDA MOTOR CO., LTD. (JP) | 2010-01-12 | — | — | US | disclosed |
| US-20090149625-A1 | AROMATIC COMPOUND HAVING FLUORENE SKELETON AND POLYARYLENE HAVING SULFONIC ACID GROUP | JSR CORPORATION (JP) | 2009-06-11 | — | — | US | disclosed |
| EP-1808461-B1 | RESIN COMPOSITION AND MOLDED OBJECT THEREOF | TEIJIN CHEMICALS LTD (JP) | 2009-03-11 | — | — | EP | disclosed |
| EP-2011812-A1 | AROMATIC COMPOUND HAVING FLUORENE SKELETON AND POLYARYLENE HAVING SULFONIC ACID GROUP | JSR Corporation (JP) | 2009-01-07 | — | — | EP | disclosed |
| US-20080085955-A1 | Resin Composition And Molded Articles Thereof | OSAKA GAS CO., LTD. (JP) | 2008-04-10 | — | — | US | disclosed |
| US-20070293606-A1 | Infrared Absorption Filter | OSAKA GAS CO., LTD. (JP) | 2007-12-20 | — | — | US | disclosed |
| US-20070248865-A1 | Membrane electrode assembly for solid polymer electrolyte fuel cell | HONDA MOTOR CO., LTD. | 2007-10-25 | — | — | US | disclosed |
| EP-1808461-A1 | RESIN COMPOSITION AND MOLDED OBJECT THEREOF | Teijin Chemicals, Ltd. (JP) | 2007-07-18 | — | — | EP | disclosed |
| EP-1804093-A1 | INFRARED ABSORBING FILTER | OSAKA GAS CO., LTD. (JP) | 2007-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149625-A1 | AROMATIC COMPOUND HAVING FLUORENE SKELETON AND POLYARYLENE HAVING SULFONIC ACID GROUP | AFF2, FGFR1, FUS | GABRA1 987/4885GABRB2 640/4885ESR1 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.