Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | CHKA | P35790 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL27935977 | 0.88 | HTT (0.58) | CHRNA7DRD2SIGMAR1MAPTNPC1 | |
| Methyl Alcohol SCHEMBL27860486 | 0.87 | MAPT (0.59) | CHRNA7DRD2SIGMAR1MAPTNPC1 | |
| SCHEMBL28105340 | 0.87 | L3MBTL1 (0.59) | CHRNA7SIGMAR1MAPTNPC1RAB9A | |
| SCHEMBL93630 | 0.87 | L3MBTL1 (0.59) | CHRNA7SIGMAR1MAPTNPC1RAB9A | |
| Cyclohexane SCHEMBL27743405 | 0.87 | L3MBTL1 (0.59) | CHRNA7SIGMAR1MAPTNPC1RAB9A | |
| SCHEMBL2312380 | 0.87 | L3MBTL1 (0.59) | CHRNA7SIGMAR1MAPTNPC1RAB9A | |
| Benzene SCHEMBL28818227 | 0.87 | L3MBTL1 (0.59) | CHRNA7SIGMAR1MAPTNPC1RAB9A | |
| SCHEMBL1968506 | 0.87 | L3MBTL1 (0.59) | CHRNA7SIGMAR1MAPTNPC1RAB9A | |
| SCHEMBL8542780 | 0.87 | L3MBTL1 (0.59) | CHRNA7SIGMAR1MAPTNPC1RAB9A | |
| Hexane SCHEMBL28857999 | 0.86 | DRD2 (0.56) | CHRNA7DRD2SIGMAR1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658719-A | Purification method of myrcene | 福州大学 | 2018-10-16 | — | — | CN | claimed |
| CN-110256995-A | A kind of flame-retardant double-component polyethers adhesive and preparation method thereof | 烟台泰盛精化科技有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110078845-A | A kind of efficient water soluble terminator and its preparation method and application for polyvinyl chloride polymers system | 乌鲁木齐市华泰隆化学助剂有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-109503890-A | Polyurethane sponge chemically composited brightening agent and preparation method | 怀化学院 | 2019-03-22 | — | — | CN | disclosed |
| CN-108218026-B | A method of processing waste water containing piperidine alcohols simultaneously recycles piperidine alcohols | 杭州九清科技有限公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-109394915-A | A kind of dedicated bacteria remover of pet | 南京海洛阿姆生物科技有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-106366656-B | A kind of high-intensitive high apparently high glass fiber reinforced nylon material and preparation method thereof | 五行科技股份有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-108569996-A | A kind of synthetic method of high-efficiency polymerization inhibitor 701 | 江苏富比亚化学品有限公司 | 2018-09-25 | — | — | CN | disclosed |
| CN-105646934-B | A kind of light stabilizer and preparation method thereof | 南通市振兴精细化工有限公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-108218026-A | A kind of method for handling waste water containing piperidine alcohols and recycling piperidine alcohols | 杭州九清科技有限公司 | 2018-06-29 | — | — | CN | disclosed |
| CN-106543498-A | A kind of automobile door sealing circle | 黄山全晟密封科技有限公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-106366656-A | High-strength and high-apparent high glass fiber reinforced nylon material and preparation method thereof | 五行科技股份有限公司 | 2017-02-01 | — | — | CN | disclosed |