Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL8693913 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KMT2ACYP2C19NPC1RAB9A | |
| SCHEMBL8694695 | 0.76 | CYP3A4 (0.42) | ALDH1A1KDM4ECYP2C19TSHR | |
| SCHEMBL10334686 | 0.74 | PPARA (0.50) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL5269658 | 0.74 | KMT2A (0.41) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL27547966 | 0.72 | SMN1; SMN2 (0.41) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL30768939 | 0.72 | PKM (0.55) | ALDH1A1KDM4EMAOBTSHRNR4A1 | |
| SCHEMBL8694822 | 0.71 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPTCYP2C19NPC1 | |
| SCHEMBL16672541 | 0.71 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2APOLBPTPN1 | |
| SCHEMBL603883 | 0.71 | CYP1A2 (0.45) | ALDH1A1CYP2C19PTPN1MAOBHIF1A | |
| SCHEMBL1357621 | 0.71 | TSHR (0.43) | ALDH1A1CYP2C19PTPN1HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106414434-A | Isothiazole derivatives as gpr120 agonists for the treatment of type ii diabetes | 詹森药业有限公司 | 2017-02-15 | — | — | CN | disclosed |