Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | UNG | P13051 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28143850 | 0.84 | LOXL2 (0.45) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL27362374 | 0.83 | KMT2A (0.40) | HSD17B10HPGDPPARAKMT2AL3MBTL1 | |
| SCHEMBL28083991 | 0.80 | CA12 (0.47) | HSD17B10CYP1A2CYP2C9HPGDCA12 | |
| SCHEMBL222176 | 0.77 | KMT2A (0.58) | HSD17B10CYP1A2CYP2C9HPGDCA12 | |
| SCHEMBL29625195 | 0.77 | KMT2A (0.58) | HSD17B10CYP1A2CYP2C9HPGDCA12 | |
| SCHEMBL27294646 | 0.77 | HTT (0.43) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL28296060 | 0.76 | HSD17B1 (0.41) | HSD17B10CYP1A2CYP2C9HPGDKMT2A | |
| SCHEMBL27761399 | 0.75 | KMT2A (0.57) | HSD17B10CYP1A2CYP2C9HPGDCA12 | |
| SCHEMBL28847949 | 0.75 | — | — | |
| SCHEMBL4642703 | 0.74 | KMO (0.50) | HSD17B10CYP1A2CYP2C9HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106470972-B | Sulfonylaminobenzamide compounds | 瑞士伊兰科动物保健有限公司 | 2019-10-18 | — | — | CN | disclosed |
| CN-106660961-A | Novel sulfonylaminobenzamide compounds as anthelmintics | 瑞士诺华动物保健有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-106470972-A | Sulfonylaminobenzamide compounds | 瑞士诺华动物保健有限公司 | 2017-03-01 | — | — | CN | disclosed |