Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24652820 | 0.78 | TSHR (0.37) | TSHRSMN1; SMN2CA2MAPTTP53 | |
| SCHEMBL21230480 | 0.75 | TSHR (0.34) | TSHRSMN1; SMN2CA2MAPTTP53 | |
| SCHEMBL9164824 | 0.73 | FDPS (0.39) | TSHRSMN1; SMN2CA2MAPTTP53 | |
| SCHEMBL6009008 | 0.73 | FAAH (0.41) | TSHRSMN1; SMN2CA2MAPTTP53 | |
| SCHEMBL2715230 | 0.72 | TP53 (0.41) | TSHRSMN1; SMN2MAPTTP53ALDH1A1 | |
| SCHEMBL18008605 | 0.71 | TP53 (0.43) | TSHRSMN1; SMN2CA2MAPTTP53 | |
| SCHEMBL28234303 | 0.71 | CA2 (0.48) | CA2TP53 | |
| SCHEMBL22176746 | 0.71 | TP53 (0.39) | TSHRCA2TP53FAAHLMNA | |
| SCHEMBL3722966 | 0.70 | EPHX1 (0.35) | TSHRSMN1; SMN2CA2MAPTTP53 | |
| Lithium Ion SCHEMBL19811155 | 0.70 | CA2 (0.34) | TSHRSMN1; SMN2CA2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115057801-A | F-18 labeled PSMA (patterned Markov chain) targeted PET (polyethylene terephthalate) probe and preparation method thereof | 西南医科大学附属医院 | 2022-09-16 | — | — | CN | claimed |
| CN-115057801-A | F-18 labeled PSMA (patterned Markov chain) targeted PET (polyethylene terephthalate) probe and preparation method thereof | 西南医科大学附属医院 | 2022-09-16 | — | — | CN | disclosed |
| CN-115057801-A | F-18 labeled PSMA (patterned Markov chain) targeted PET (polyethylene terephthalate) probe and preparation method thereof | 西南医科大学附属医院 | 2022-09-16 | — | — | CN | disclosed |