Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29721481 | 0.69 | MMP1 (0.50) | ALDH1A1KDM4ECYP1A2POLBCYP3A4 | |
| SCHEMBL29721614 | 0.68 | KDM4E (0.42) | DPP4DPP8DPP7PLGALDH1A1 | |
| SCHEMBL31053369 | 0.65 | PLG (0.52) | PLGALDH1A1KDM4ECYP1A2POLB | |
| SCHEMBL10847635 | 0.62 | PLG (0.37) | DPP4DPP8DPP7PLGALDH1A1 | |
| SCHEMBL13719433 | 0.62 | CMA1 (0.41) | PLGALDH1A1KDM4ECYP1A2POLB | |
| SCHEMBL13859661 | 0.62 | PLG (0.42) | DPP4PLGALDH1A1KDM4ECYP1A2 | |
| SCHEMBL30098315 | 0.62 | ALDH1A1 (0.50) | ALDH1A1SIGMAR1SMN1; SMN2MEN1MAPK1 | |
| SCHEMBL1124265 | 0.62 | ALDH1A1 (0.50) | ALDH1A1SIGMAR1SMN1; SMN2MEN1MAPK1 | |
| SCHEMBL22453817 | 0.61 | AOC3 (0.39) | PLGALDH1A1KDM4ECYP1A2POLB | |
| SCHEMBL469052 | 0.61 | HTR2A (0.61) | PLGPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736197-B | Imidazolidinone derivatives and their use | 南京医工医药技术有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-114736197-A | Imidazolidinone derivatives and their use | 南京医工医药技术有限公司 | 2022-07-12 | — | — | CN | disclosed |