Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 17/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | CLK2 | P49760 | 8/20 | 0.41 |
| ▸ | CLK3 | P49761 | 8/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | WNT1 | P04628 | 6/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28127556 | 0.86 | WNT1 (0.46) | DYRK1AGSK3BCLK2CLK3DRD2 | |
| SCHEMBL28291114 | 0.86 | WNT1 (0.46) | DYRK1AGSK3BCLK2CLK3DRD2 | |
| SCHEMBL28291102 | 0.86 | WNT1 (0.46) | DYRK1AGSK3BCLK2CLK3DRD2 | |
| SCHEMBL28127395 | 0.85 | WNT1 (0.47) | DYRK1AGSK3BCLK2CLK3DRD2 | |
| SCHEMBL28839806 | 0.84 | DYRK1A (0.51) | DYRK1AGSK3BCLK2CLK3DRD2 | |
| SCHEMBL28952966 | 0.84 | DYRK1A (0.45) | DYRK1AGSK3BCLK2CLK3DRD2 | |
| SCHEMBL28127518 | 0.83 | WNT1 (0.48) | DYRK1AGSK3BCLK2CLK3DRD2 | |
| SCHEMBL28127717 | 0.83 | DRD2 (0.51) | DYRK1AGSK3BCLK2CLK3DRD2 | |
| SCHEMBL28127439 | 0.82 | WNT1 (0.49) | DYRK1AGSK3BCLK2CLK3DRD2 | |
| SCHEMBL28839832 | 0.82 | NR3C1 (0.40) | DYRK1AWNT1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106535890-A | 5-substituted indazole-3-carboxamides and preparation and use thereof | 萨穆梅德有限公司 | 2017-03-22 | — | — | CN | claimed |