Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 4/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17673857 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2RAB9ANPC1HPGDMEN1 | |
| SCHEMBL9138719 | 0.78 | NPC1 (0.44) | SMN1; SMN2RAB9ANPC1HPGDMEN1 | |
| SCHEMBL19065262 | 0.75 | GPR55 (0.41) | SMN1; SMN2RAB9ANPC1HPGDMEN1 | |
| SCHEMBL1422766 | 0.72 | ALDH1A1 (0.43) | SMN1; SMN2HPGDMEN1KMT2ACYP2C9 | |
| SCHEMBL4978950 | 0.71 | RAB9A (0.43) | SMN1; SMN2RAB9ANPC1HPGDMEN1 | |
| SCHEMBL2415309 | 0.71 | EPHX2 (0.58) | SMN1; SMN2RAB9ANPC1HPGDMEN1 | |
| SCHEMBL3077834 | 0.70 | HPGD (0.50) | SMN1; SMN2RAB9ANPC1HPGDMEN1 | |
| SCHEMBL2576181 | 0.69 | NPC1 (0.38) | SMN1; SMN2RAB9ANPC1HPGDMEN1 | |
| SCHEMBL1903692 | 0.69 | PDK2 (0.48) | SMN1; SMN2RAB9ANPC1HPGDMEN1 | |
| SCHEMBL9134585 | 0.68 | ALDH1A1 (0.43) | SMN1; SMN2RAB9ANPC1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243971-A1 | NOVEL COMPOUNDS AND THEIR METHODS OF USE THEREOF | FOUNDATION FOR NEGLECTED DISEASE RESEARCH (IN) | 2019-12-26 | — | — | WO | claimed |
| US-20100283386-A1 | DISPLAY DEVICE AND COMPOSITION FOR PRODUCING DISPLAY DEVICE, AND DISPLAY DEVICE | SONY CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| CN-1925833-A | Keratin dyeing compounds, keratin dyeing compositions containing them, and their use | PROCTER & GAMBLE (US) | 2007-03-07 | — | — | CN | disclosed |
| US-5387657-A | Liquid crystal polymers; high glass transition temperatures; enhanced unidirectional mechanical properties; coatings, castings, encapsulation, lamination, composites, molding materials | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | disclosed |
| WO-1994025501-A1 | EPOXY RESINS CONTAINING THIADIAZOLE AND/OR OXADIAZOLE MOIETIES | THE DOW CHEMICAL COMPANY (US) | 1994-11-10 | — | — | WO | disclosed |
| US-5290887-A | Liquid crystal polymers for coatings, castings, encapsulation, electronics or laminates | THE DOW CHEMICAL COMPANY (US) | 1994-03-01 | — | — | US | disclosed |