Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2191780 | 0.82 | APP (0.52) | APPMAPTGRM5CYP1A2CYP3A4 | |
| SCHEMBL717633 | 0.74 | APP (0.67) | APPMAPTADKGRM5PTGDR2 | |
| SCHEMBL8093294 | 0.73 | KCNH2 (0.50) | APPMAPTADKGRM5CYP1A2 | |
| SCHEMBL1822569 | 0.71 | APP (0.55) | APPMAPTGRM5CYP1A2CYP3A4 | |
| SCHEMBL21858052 | 0.69 | APP (0.46) | APPMAPTGRM5CYP1A2CYP3A4 | |
| SCHEMBL2189677 | 0.69 | APP (0.46) | APPMAPTGRM5PTGDR2CYP1A2 | |
| SCHEMBL5133632 | 0.69 | CYP1A2 (0.64) | APPMAPTADKGRM5CYP1A2 | |
| SCHEMBL352270 | 0.69 | — | — | |
| Diphenylacetylene SCHEMBL29188592 | 0.68 | APP (1.00) | APPMAPTGRM5CYP1A2CYP3A4 | |
| Diphenylacetylene SCHEMBL960609 | 0.68 | APP (1.00) | APPMAPTGRM5CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115044923-B | Method for preparing 2-aryl-3-thiocyano-benzothiophene by utilizing electrochemical reaction | 盐城师范学院 | 2023-05-05 | — | — | CN | disclosed |
| CN-115044923-A | Method for preparing 2-aryl-3-thiocyano-benzothiophene by using electrochemical reaction | 盐城师范学院 | 2022-09-13 | — | — | CN | disclosed |