SCHEMBL717633

SCHEMBL717633

Clc1ccc(C#Cc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.67
MAPT P10636 2/20 0.56
KCNH2 Q12809 2/20 0.54
TSHR P16473 1/20 0.53
CYP1A2 P05177 3/20 0.50
GRM5 P41594 2/20 0.48
ADK P55263 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
FFAR1 O14842 3/20 0.45
CYP3A4 P08684 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
LMNA P02545 1/20 0.44
CYP2A6 P11509 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5133632 0.93 CYP1A2 (0.64) APPMAPTKCNH2TSHRCYP1A2
SCHEMBL20015814 0.88 LMNA (0.57) APPMAPTKCNH2TSHRCYP1A2
SCHEMBL719360 0.88 LMNA (0.57) APPMAPTKCNH2TSHRCYP1A2
Charcoal, Activated SCHEMBL31286310 0.85 KCNH2 (0.54) APPMAPTKCNH2TSHRCYP1A2
SCHEMBL2114741 0.85 APP (0.92) APPMAPTKCNH2TSHRCYP1A2
SCHEMBL3839221 0.83 TSHR (0.53) APPMAPTKCNH2TSHRCYP1A2
SCHEMBL4358220 0.83 SRD5A2 (0.59) APPMAPTTSHRFFAR1LMNA
SCHEMBL4589734 0.83 ALDH1A1 (0.61) APPMAPTKCNH2CA12CA1
Diphenylacetylene SCHEMBL960609 0.82 APP (1.00) APPMAPTKCNH2TSHRCYP1A2
Diphenylacetylene SCHEMBL29188592 0.82 APP (1.00) APPMAPTKCNH2TSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4554797-A1 ANTI-COUNTERFEITING LABEL FOR THE AUTHENTICATION OF GOODS Politecnico di Milano (IT) 2025-05-21 EP claimed
CN-117845235-A Preparation method of cis-stilbene compound 深圳市环保科技集团股份有限公司 2024-04-09 CN claimed
WO-2024013693-A1 ANTI-COUNTERFEITING LABEL FOR THE AUTHENTICATION OF GOODS POLITECNICO DI MILANO (IT) 2024-01-18 WO claimed
EP-2284222-A2 Semiconductor composition Xerox Corporation (US) 2011-02-16 EP claimed
US-20110031475-A1 Semiconductor Composition XEROX CORPORATION (US) 2011-02-10 US claimed
EP-1502292-A4 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE INC (US) 2009-01-21 EP claimed
JP-2005524240-A 2005-08-11 JP claimed
US-6852474-B2 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE INC. (US) 2005-02-08 US claimed
EP-1502292-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION Brewer Science, Inc. (US) 2005-02-02 EP claimed
US-20030224586-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-12-04 US claimed
WO-2003094213-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE, INC. (US) 2003-11-13 WO claimed
CN-116410126-B Ligand, ruthenium complex, preparation method thereof and application of ligand and ruthenium complex in catalyzing alkyne semi-hydrogenation reaction 河北师范大学 2025-05-09 CN disclosed
CN-117845235-A Preparation method of cis-stilbene compound 深圳市环保科技集团股份有限公司 2024-04-09 CN disclosed
CN-117843428-A endo/exo 3, 4-disubstituted tricyclo [4.2.1.0 2,5 ]Process for preparing non-3, 7-diene compound 湖南师范大学 2024-04-09 CN disclosed
CN-117466695-A Cobalt-catalyzed alkyne synthesis method 合肥工业大学 2024-01-30 CN disclosed
WO-2003094213-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE, INC. (US) 2003-11-13 WO disclosed
US-6020519-A Diphenyl-cyclopropenes as selective K-agonists WARNER-LAMBERT COMPANY (US) 2000-02-01 US disclosed
US-5968968-A Diphenyl-cyclopropenes as selective K-agonists WARNER-LAMBERT COMPANY (US) 1999-10-19 US disclosed
US-5886240-A Process for preparing aromatic acetylenes using palladacycles as catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1999-03-23 US disclosed
WO-1998003491-A1 DIPHENYL-CYCLOPROPENES AS SELECTIVE K-AGONISTS WARNER-LAMBERT COMPANY (US) 1998-01-29 WO disclosed