Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.50 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1822569 | 0.84 | APP (0.55) | KCNH2GRM5APPMAPTCYP1A2 | |
| SCHEMBL5586491 | 0.81 | APP (0.36) | KCNH2GRM5APPMAPT | |
| SCHEMBL5403604 | 0.77 | ALDH1A1 (0.47) | KCNH2GRM5APPMAPTCYP1A2 | |
| SCHEMBL5494749 | 0.77 | APP (0.32) | KCNH2APPMAPT | |
| SCHEMBL8988350 | 0.77 | TRPA1 (0.39) | KCNH2APPMAPTTSHR | |
| SCHEMBL6514875 | 0.75 | RARB (0.47) | GRM5TSHRACACB | |
| SCHEMBL21858024 | 0.74 | ASIC3 (0.40) | GRM5CYP1A2CYP2A6ACACB | |
| SCHEMBL5268395 | 0.74 | CA2 (0.42) | APPTSHR | |
| SCHEMBL717633 | 0.74 | APP (0.67) | KCNH2GRM5APPMAPTADK | |
| SCHEMBL20015814 | 0.73 | LMNA (0.57) | KCNH2GRM5APPMAPTADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117203556-A | High refractive index and high birefringence solid organic material | 元平台技术有限公司 | 2023-12-08 | — | — | CN | disclosed |
| EP-1051394-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037607-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 1999-07-29 | — | — | WO | disclosed |