Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852050 | 1.00 | RAB9A (0.40) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL28922177 | 0.83 | GAA (0.49) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL31519906 | 0.82 | KDM4E (0.49) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL29851968 | 0.81 | NPC1 (0.51) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL28840648 | 0.81 | NPC1 (0.51) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL8980162 | 0.77 | KDM4E (0.47) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL3735091 | 0.76 | NPC1 (0.38) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL197110 | 0.74 | SOS1 (0.50) | KMT2AKDM4EL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL6058046 | 0.74 | CYP3A4 (0.46) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL11226829 | 0.72 | PTK6 (0.46) | RAB9ANPC1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867758-A | IRAK degradation agents and uses thereof | 凯麦拉医疗公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116133692-A | Methods of treating mutant lymphomas | 凯麦拉医疗公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-115052627-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2022-09-13 | — | — | CN | disclosed |