SCHEMBL28840672

SCHEMBL28840672

CCC(=O)Cc1cccc(OC)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.55
PTGS2 P35354 1/20 0.55
IDO1 P14902 1/20 0.53
CALM1 P0DP23 1/20 0.53
ALDH1A1 P00352 2/20 0.48
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.48
LMNA P02545 1/20 0.48
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
MAPK1 P28482 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ANO1 Q5XXA6 1/20 0.47
GAA P10253 2/20 0.46
GFER P55789 1/20 0.46
IAPP P10997 1/20 0.45
TLR2 O60603 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4479762 0.84 KMT2A (0.54) MAPTLMNACYP3A4GAAATM
SCHEMBL28235226 0.83 IDO1 (0.60) ALOX5PTGS2IDO1CALM1ALDH1A1
SCHEMBL2874758 0.83 IDO1 (0.56) ALOX5PTGS2IDO1CALM1ALDH1A1
SCHEMBL9576160 0.82 ALOX5 (0.66) ALOX5PTGS2IDO1CALM1ALDH1A1
SCHEMBL23229160 0.81 ALOX5 (0.53) ALOX5PTGS2IDO1CALM1ALDH1A1
Ethylene SCHEMBL7414807 0.80 KDM4E (0.40) IDO1ALDH1A1KDM4ELMNACYP3A4
SCHEMBL5786432 0.79 ALOX5 (0.54) ALOX5PTGS2IDO1CALM1ALDH1A1
SCHEMBL5786427 0.79 ALOX5 (0.54) ALOX5PTGS2IDO1CALM1ALDH1A1
SCHEMBL28919444 0.79 FASN (0.40) CYP3A4HSD17B10GAA
Phenol SCHEMBL29930302 0.78 LMNA (0.49) ALOX5PTGS2IDO1CALM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106478394-A A kind of preparation technology of 1 (2 hydroxyl, 3 anisyl) ethyl ketone 贵州大学 2017-03-08 CN disclosed