SCHEMBL28840708

SCHEMBL28840708

CCOC(=O)C(=O)c1ccn(CCC2(C(=O)OC)CCCCC2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
MAPT P10636 2/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
KDM4E B2RXH2 1/20 0.32
PKM P14618 2/20 0.31
POLB P06746 2/20 0.31
LMNA P02545 2/20 0.31
ALDH1A1 P00352 3/20 0.31
HPGD P15428 1/20 0.31
OPRM1 P35372 2/20 0.31
OPRD1 P41143 2/20 0.31
SLC22A1 O15245 1/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31
OPRK1 P41145 1/20 0.31
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28840768 0.80 CYP4F2 (0.37) CYP4F2CYP4A11MEN1KMT2AMAPT
SCHEMBL28840683 0.74 HTT (0.39) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL28840813 0.69 CA12 (0.39) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL28840752 0.66 DUT (0.37) MAPTATML3MBTL1ALDH1A1HTT
SCHEMBL28199817 0.62 CYP4F2 (0.67) CYP4F2CYP4A11MEN1KMT2AMAPT
SCHEMBL8278881 0.62 CYP4F2 (0.71) CYP4F2CYP4A11MEN1KMT2AMAPT
SCHEMBL27994909 0.62 MEN1 (0.49) CYP4F2CYP4A11MEN1KMT2AMAPT
SCHEMBL17857 0.61 CYP4F2 (0.55) CYP4F2CYP4A11MEN1KMT2AMAPT
SCHEMBL8311121 0.61 CYP4F2 (0.44) CYP4F2CYP4A11MEN1KMT2AMAPT
SCHEMBL2235513 0.61 CYP4F2 (0.70) CYP4F2CYP4A11MAPTP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907389-A Boronic acid derivatives 首药控股(北京)股份有限公司 2022-08-16 CN disclosed