Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28840752 | 0.78 | DUT (0.37) | HTTATML3MBTL1ALDH1A1MAPT | |
| SCHEMBL28840708 | 0.74 | CYP4F2 (0.37) | HTTATML3MBTL1ALDH1A1MAPT | |
| SCHEMBL22748664 | 0.74 | CYP4A11 (0.44) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL28840813 | 0.73 | CA12 (0.39) | HTTATML3MBTL1ALDH1A1MAPT | |
| SCHEMBL17420558 | 0.72 | BAZ2B (0.43) | HTTATML3MBTL1ALDH1A1MAPT | |
| SCHEMBL31701380 | 0.72 | CA12 (0.47) | L3MBTL1ALDH1A1MAPTCA12CA1 | |
| SCHEMBL4768985 | 0.72 | CA12 (0.46) | HTTALDH1A1MAPTCA12CA1 | |
| SCHEMBL4591254 | 0.71 | HTT (0.37) | HTTATML3MBTL1ALDH1A1MAPT | |
| SCHEMBL13531603 | 0.70 | ALDH1A1 (0.49) | HTTALDH1A1MAPTCA12CA1 | |
| SCHEMBL18019122 | 0.70 | LMNA (0.50) | HTTL3MBTL1ALDH1A1MAPTPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907389-A | Boronic acid derivatives | 首药控股(北京)股份有限公司 | 2022-08-16 | — | — | CN | disclosed |