SCHEMBL28840717

SCHEMBL28840717

CC(C)n1nccc1-c1ccccc1P(C(C)(C)C)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
USP1 O94782 3/20 0.33
NR3C2 P08235 1/20 0.33
PRMT5 O14744 1/20 0.30
WDR77 Q9BQA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28953076 0.82 USP1 (0.36) USP1NR3C2PRMT5WDR77
SCHEMBL28840670 0.74 ATR (0.32) USP1NR3C2PRMT5WDR77
SCHEMBL29790494 0.74 ATR (0.32) USP1NR3C2PRMT5WDR77
SCHEMBL25258575 0.73 IDO1 (0.44) NR3C2PRMT5WDR77
SCHEMBL28840712 0.73 NR3C2 (0.36) USP1NR3C2PRMT5WDR77
SCHEMBL333685 0.71 ALDH1A1 (0.30)
SCHEMBL29492107 0.71 ALDH1A1 (0.30)
SCHEMBL12277396 0.69 NR3C2 (0.46) USP1NR3C2PRMT5WDR77
SCHEMBL30883947 0.68 NR3C2 (0.40) NR3C2
SCHEMBL4008294 0.66 CA1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907404-B 5- (2- (Disubstituted phosphino) phenyl) -1-alkyl-1H-pyrazolyl phosphine ligand and preparation method and application thereof 香港理工大学深圳研究院 2024-05-14 CN disclosed
CN-114907404-A 5- (2- (disubstituted phosphino) phenyl) -1-alkyl-1H-pyrazolylphosphine ligand and preparation method and application thereof 香港理工大学深圳研究院 2022-08-16 CN disclosed