Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | USP1 | O94782 | 3/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25258575 | 0.79 | IDO1 (0.44) | NR3C2MAPK1ALDH1A1PRMT5WDR77 | |
| SCHEMBL15202358 | 0.77 | COMT (0.43) | MAPK1ALDH1A1NPC1HSD11B1RAB9A | |
| SCHEMBL29790460 | 0.77 | COMT (0.43) | MAPK1ALDH1A1NPC1HSD11B1RAB9A | |
| SCHEMBL28953076 | 0.76 | USP1 (0.36) | NR3C2USP1PRMT5WDR77 | |
| SCHEMBL20547887 | 0.74 | NR3C2 (0.33) | NR3C2NPC1 | |
| SCHEMBL12277396 | 0.74 | NR3C2 (0.46) | NR3C2ALDH1A1NPC1RAB9AUSP1 | |
| SCHEMBL30883947 | 0.73 | NR3C2 (0.40) | NR3C2 | |
| SCHEMBL28840717 | 0.73 | USP1 (0.33) | NR3C2USP1PRMT5WDR77 | |
| SCHEMBL28840689 | 0.72 | ADRA1A (0.47) | MAPK1ALDH1A1NPC1HSD11B1RAB9A | |
| SCHEMBL19738062 | 0.71 | ALDH1A1 (0.42) | NR3C2ALDH1A1USP1PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907404-B | 5- (2- (Disubstituted phosphino) phenyl) -1-alkyl-1H-pyrazolyl phosphine ligand and preparation method and application thereof | 香港理工大学深圳研究院 | 2024-05-14 | — | — | CN | disclosed |
| CN-114907404-A | 5- (2- (disubstituted phosphino) phenyl) -1-alkyl-1H-pyrazolylphosphine ligand and preparation method and application thereof | 香港理工大学深圳研究院 | 2022-08-16 | — | — | CN | disclosed |