Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27582186 | 0.86 | ENPP2 (0.37) | ENPP2MMP3KDM4ETDP1KIF11 | |
| SCHEMBL29790934 | 0.86 | ENPP2 (0.37) | ENPP2MMP3KDM4ETDP1KIF11 | |
| SCHEMBL4521078 | 0.78 | ENPP2 (0.39) | ENPP2MMP3KDM4ETDP1TSHR | |
| SCHEMBL21382504 | 0.77 | PRMT5 (0.38) | PRMT5WDR77PIK3CD | |
| SCHEMBL28840799 | 0.77 | PRMT5 (0.38) | PRMT5WDR77PIK3CD | |
| SCHEMBL21382554 | 0.77 | PRMT5 (0.40) | PRMT5WDR77PIK3CD | |
| SCHEMBL9123053 | 0.77 | PRMT5 (0.38) | PRMT5WDR77KDM4ENPC1RAB9A | |
| SCHEMBL1466419 | 0.77 | RXRB (0.40) | ENPP2MMP3KDM4ETDP1NPC1 | |
| SCHEMBL8089040 | 0.75 | RAB9A (0.44) | NPC1RAB9A | |
| SCHEMBL3642604 | 0.75 | CHRM2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907389-A | Boronic acid derivatives | 首药控股(北京)股份有限公司 | 2022-08-16 | — | — | CN | disclosed |