Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28922903 | 0.81 | KDM4E (0.35) | TP53CREBBPKDM4EALDH1A1CYP1A2 | |
| SCHEMBL28840719 | 0.74 | TERT (0.47) | TP53CREBBPMTNR1AMTNR1BKDM4E | |
| SCHEMBL16201684 | 0.72 | CDK5 (0.45) | TP53CREBBPMTNR1AMTNR1BKDM4E | |
| SCHEMBL10725922 | 0.72 | KDM4E (0.54) | TP53CREBBPMTNR1AMTNR1BKDM4E | |
| SCHEMBL9471252 | 0.71 | MTNR1A (0.46) | TP53CREBBPMTNR1AMTNR1BKDM4E | |
| SCHEMBL7384938 | 0.67 | MTNR1A (0.41) | TP53CREBBPMTNR1AMTNR1BKDM4E | |
| SCHEMBL18202181 | 0.65 | PABPC1 (0.49) | TP53CREBBPMTNR1AMTNR1BKDM4E | |
| SCHEMBL7321799 | 0.63 | HTR2A (0.52) | KDM4EALDH1A1HSD17B10ALOX15MEN1 | |
| SCHEMBL31486786 | 0.63 | HTR2A (0.52) | KDM4EALDH1A1HSD17B10ALOX15MEN1 | |
| SCHEMBL16201678 | 0.63 | PABPC1 (0.46) | TP53CREBBPMTNR1AMTNR1BPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907389-A | Boronic acid derivatives | 首药控股(北京)股份有限公司 | 2022-08-16 | — | — | CN | disclosed |