Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832541 | 0.81 | KMT2A (0.67) | KMT2ANPC1RAB9ARNASEH1PKM | |
| SCHEMBL29569183 | 0.81 | KMT2A (0.67) | KMT2ANPC1RAB9ARNASEH1PKM | |
| Hydrochloric Acid SCHEMBL4557636 | 0.80 | KMT2A (0.65) | KMT2ANPC1RAB9ARNASEH1PKM | |
| Diftalone SCHEMBL35351 | 0.76 | KMT2A (1.00) | KMT2ANPC1RAB9ARNASEH1PKM | |
| Diftalone SCHEMBL29644941 | 0.76 | KMT2A (1.00) | KMT2ANPC1RAB9ARNASEH1PKM | |
| SCHEMBL31352634 | 0.76 | KMT2A (0.59) | KMT2ANPC1RAB9ARNASEH1PKM | |
| Formic Acid SCHEMBL38654533 | 0.75 | KMT2A (0.57) | KMT2ANPC1RAB9ARNASEH1PKM | |
| SCHEMBL28411858 | 0.72 | KMT2A (0.54) | KMT2ANPC1RAB9ARNASEH1PKM | |
| SCHEMBL30736409 | 0.71 | KMT2A (0.61) | KMT2ANPC1RAB9ARNASEH1PKM | |
| Trifluoroacetic Acid SCHEMBL30727536 | 0.71 | KMT2A (0.51) | KMT2ANPC1RAB9ARNASEH1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115038448-A | Compounds that modulate protein recruitment and/or degradation | 奥里尼斯生物科学股份有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-112638380-B | Cerebellar protein (CRBN) ligands | 达纳-法伯癌症研究所有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-115038448-A | Compounds that modulate protein recruitment and/or degradation | 奥里尼斯生物科学股份有限公司 | 2022-09-09 | — | — | CN | disclosed |