Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29569183 | 0.79 | KMT2A (0.67) | KMT2ARAB9ANPC1RNASEH1PKM | |
| SCHEMBL23832541 | 0.79 | KMT2A (0.67) | KMT2ARAB9ANPC1RNASEH1PKM | |
| Hydrochloric Acid SCHEMBL4557636 | 0.78 | KMT2A (0.65) | KMT2ARAB9ANPC1RNASEH1PKM | |
| Diftalone SCHEMBL35351 | 0.77 | KMT2A (1.00) | KMT2ARAB9ANPC1RNASEH1PKM | |
| Diftalone SCHEMBL29644941 | 0.77 | KMT2A (1.00) | KMT2ARAB9ANPC1RNASEH1PKM | |
| SCHEMBL28411858 | 0.77 | KMT2A (0.54) | KMT2ARAB9ANPC1RNASEH1PKM | |
| Formic Acid SCHEMBL38654533 | 0.73 | KMT2A (0.57) | KMT2ARAB9ANPC1RNASEH1PKM | |
| SCHEMBL31352634 | 0.71 | KMT2A (0.59) | KMT2ARAB9ANPC1RNASEH1PKM | |
| SCHEMBL28840917 | 0.71 | KMT2A (0.59) | KMT2ARAB9ANPC1RNASEH1PKM | |
| SCHEMBL31019490 | 0.70 | KMT2A (0.63) | KMT2ARAB9ANPC1RNASEH1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355759-A1 | POPULATIONS OF NATURAL KILLER CELLS COMPRISING A CLEAVAGE RESISTANT CD16 | CELULARITY INC. (US) | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230355759-A1 | POPULATIONS OF NATURAL KILLER CELLS COMPRISING A CLEAVAGE RESISTANT CD16 | PBK, KLKB1, PIGK | KMT2A 1363/4885RAB9A 4294/4885NPC1 1984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.