Cyclohexane

Cyclohexane

SCHEMBL28840941

C1CCCCC1.CC(C)CCc1ccc(C(=O)O)c(C(=O)O)c1CCC(C)C

nearest known ligand 0.34

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 4/20 0.34
HDAC4 P56524 4/20 0.34
HDAC1 Q13547 4/20 0.34
HDAC7 Q8WUI4 4/20 0.34
HDAC2 Q92769 4/20 0.34
HDAC10 Q969S8 4/20 0.34
HDAC11 Q96DB2 4/20 0.34
HDAC8 Q9BY41 4/20 0.34
HDAC6 Q9UBN7 4/20 0.34
HDAC9 Q9UKV0 4/20 0.34
HDAC5 Q9UQL6 4/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM6B O15054 1/20 0.32
KDM4C Q9H3R0 1/20 0.32
MAPK1 P28482 1/20 0.32
BRS3 P32247 1/20 0.32
GRIN2D O15399 1/20 0.31
GRIN2A Q12879 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL541844 0.95 HDAC3 (0.36) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL722646 0.88 GRIN2D (0.40) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL722645 0.88 GRIN2D (0.40) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL19667966 0.86 ALDH1A1 (0.33) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL16295022 0.85 PPARA (0.45) ALDH1A1KDM4EHSD17B10MCL1
SCHEMBL8022683 0.84 HDAC3 (0.32) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL2272942 0.84 ALDH1A1 (0.32) ALDH1A1FOLH1
SCHEMBL634123 0.84 GRIN2D (0.40) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL721060 0.83 PPARA (0.44) ALDH1A1MCL1
SCHEMBL721851 0.83 PPARA (0.44) ALDH1A1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106565472-A Cyclohexanecarboxylic acid ester preparation method 万华化学集团股份有限公司 2017-04-19 CN disclosed