SCHEMBL2884280

SCHEMBL2884280

CCC(O)C(C(=O)O)=C(C(=O)O)C(O)CC

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
GPR84 Q9NQS5 3/20 0.36
FFAR1 O14842 1/20 0.36
FFAR3 O14843 1/20 0.35
OR51E2 Q9H255 1/20 0.35
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2884275 1.00 TSHR (0.36) TSHRGPR84FFAR1FFAR3OR51E2
SCHEMBL502499 0.77
Oxalic Acid SCHEMBL28235580 0.77 OR51E2 (0.48) GPR84FFAR1OR51E2TP53
SCHEMBL9599979 0.77 TSHR (0.36) TSHRGPR84FFAR1FFAR3OR51E2
SCHEMBL10884141 0.76 FNTA (0.44) GPR84FFAR1TP53
SCHEMBL193026 0.75
SCHEMBL15355768 0.75
SCHEMBL264859 0.75
SCHEMBL6963 0.75
SCHEMBL15717118 0.75 OR51E2 (0.53) GPR84FFAR1OR51E2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10034960-B2 Compositions and methods for making biodegradable structures UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2018-07-31 US disclosed
US-20160136326-A1 COMPOSITIONS AND METHODS FOR MAKING BIODEGRADABLE STRUCTURES UNIVERSITY OF MARYLAND, COLLEGE PARK 2016-05-19 US disclosed
WO-2014197790-A1 COMPOSITIONS AND METHODS FOR MAKING BIODEGRADABLE STRUCTURES UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2014-12-11 WO disclosed
US-7816461-B2 Block copolymers of polycarpolactone and poly (propylene funarate) NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-10-19 US disclosed
US-20080004368-A1 Block Copolymers of Polycarpolactone and Poly (Propylene Funarate) NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-01-03 US disclosed
US-4572869-A Microcapsular opacifiers and method for their production PPG INDUSTRIES, INC. (US) 1986-02-25 US disclosed
US-4064087-A WITHOUT BUFFERS, FREE RADICAL CATALYSTS, ADDITION POLYMERIZATION ON PPG INDUSTRIES, INC. (US) 1977-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080004368-A1 Block Copolymers of Polycarpolactone and Poly (Propylene Funarate) PLOD1, FGB, PLOD2 TSHR 4476/4885GPR84 4039/4885FFAR1 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.