Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7636675 | 0.89 | MRGPRX4 (0.57) | MAPTMAPK1TDP1L3MBTL1MRGPRX4 | |
| SCHEMBL7641375 | 0.88 | NPC1 (0.53) | MAPTMAPK1TDP1L3MBTL1MRGPRX4 | |
| SCHEMBL5339466 | 0.86 | PTPN1 (0.56) | MAPTMAPK1TDP1L3MBTL1MRGPRX4 | |
| Hydrochloric Acid SCHEMBL29175079 | 0.85 | MAPT (0.45) | MAPTMAPK1TDP1L3MBTL1MRGPRX4 | |
| SCHEMBL5345373 | 0.85 | HTR1A (0.51) | MAPTMAPK1TDP1L3MBTL1MRGPRX4 | |
| SCHEMBL3804975 | 0.81 | NPC1 (0.54) | MAPTMAPK1TDP1L3MBTL1MRGPRX4 | |
| SCHEMBL2326814 | 0.78 | PTPN1 (0.47) | MAPTMAPK1TDP1L3MBTL1MRGPRX4 | |
| SCHEMBL7195121 | 0.76 | KDM4E (0.52) | MAPTMAPK1TDP1L3MBTL1MRGPRX4 | |
| SCHEMBL6557586 | 0.75 | KDM4E (0.52) | TDP1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL11656656 | 0.75 | MEN1 (0.47) | MAPTL3MBTL1MRGPRX4HTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427451-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BioLab Corporation (JP) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128685-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2010-11-11 | — | — | WO | disclosed |