Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641375 | 0.90 | NPC1 (0.53) | MRGPRX4HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL288436 | 0.89 | MAPT (0.46) | MRGPRX4HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL5339466 | 0.89 | PTPN1 (0.56) | MRGPRX4HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL5345373 | 0.87 | HTR1A (0.51) | MRGPRX4HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7195121 | 0.87 | KDM4E (0.52) | MRGPRX4HTR1AADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL29175079 | 0.85 | MAPT (0.45) | MRGPRX4HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL15558253 | 0.85 | L3MBTL1 (0.46) | MRGPRX4L3MBTL1MAPTMAPK1KDM4E | |
| SCHEMBL3804975 | 0.83 | NPC1 (0.54) | MRGPRX4HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6055987 | 0.82 | ALDH1A1 (0.47) | L3MBTL1MAPTMAPK1LMNAGLA | |
| SCHEMBL7617609 | 0.81 | ALDH1A1 (0.46) | L3MBTL1MAPTMAPK1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020177726-A1 | Process for the preparation of 3-aryl-2-hydroxy propanoic acid | DR. REDDY'S RESEARCH FOUNDATION | 2002-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020177726-A1 | Process for the preparation of 3-aryl-2-hydroxy propanoic acid | HPD, HAO1, HAAO | MRGPRX4 3595/4885HTR1A 169/4885ADRA1D 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.