SCHEMBL28843992

SCHEMBL28843992

CC[Si](CC)(CC)OC(C)(C)c1ccccc1Br

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA5A P35218 1/20 0.33
CA9 Q16790 1/20 0.33
RIPK1 Q13546 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30675545 0.76 CA1 (0.33) HSD11B1CA1CA2CA5ACA9
SCHEMBL30675543 0.76 CA1 (0.33) HSD11B1CA1CA2CA5ACA9
SCHEMBL24538833 0.76 CA1 (0.33) HSD11B1CA1CA2CA5ACA9
SCHEMBL2059025 0.69 CA1 (0.33) CA1CA2CA5ACA9ALDH1A1
SCHEMBL10608749 0.69 RIPK1 (0.39) HSD11B1CA1CA2CA5ACA9
SCHEMBL6441340 0.69 RIPK1 (0.39) HSD11B1CA1CA2CA5ACA9
SCHEMBL21580260 0.68 NOTUM (0.35)
SCHEMBL5080120 0.67 ALDH1A1 (0.43) HSD11B1CA1CA2CA5ACA9
SCHEMBL292047 0.67 ALDH1A1 (0.50) HSD11B1CA1CA2CA5ACA9
SCHEMBL9275642 0.67 ALDH1A1 (0.43) HSD11B1CA1CA2CA5ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110526802-B Monomer, polymer, negative resist composition, photomask blank, and resist pattern forming method 信越化学工业株式会社 2022-09-20 CN disclosed