SCHEMBL24538833

SCHEMBL24538833

CC(C)(O[Si](C)(C)C(C)(C)C)c1ccccc1Br

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA5A P35218 1/20 0.33
CA9 Q16790 1/20 0.33
ALDH1A1 P00352 1/20 0.31
HSD11B1 P28845 1/20 0.31
PDE2A O00408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30675543 1.00 CA1 (0.33) CA1CA2CA5ACA9ALDH1A1
SCHEMBL30675545 1.00 CA1 (0.33) CA1CA2CA5ACA9ALDH1A1
SCHEMBL28843992 0.76 HSD11B1 (0.33) CA1CA2CA5ACA9ALDH1A1
SCHEMBL24539194 0.76 GLA (0.31)
SCHEMBL24539369 0.73 ENPP2 (0.33) CA1CA2
SCHEMBL24539189 0.73 ENPP2 (0.33) CA1CA2
SCHEMBL5080120 0.73 ALDH1A1 (0.43) CA1CA2CA5ACA9ALDH1A1
SCHEMBL24539375 0.72 LPL (0.35) CA1CA2CA9
SCHEMBL24539190 0.72 LPL (0.35) CA1CA2CA9
SCHEMBL26811639 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117242080-A Boron-containing pyrazole compounds, compositions comprising the same, methods and uses thereof 勃林格殷格翰动物保健美国公司 2023-12-15 CN disclosed
US-11827657-B2 Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof Boehringer Ingelheim Animal Health USA Inc. (US) 2023-11-28 US disclosed
US-11827657-B2 Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof Boehringer Ingelheim Animal Health USA Inc. (US) 2023-11-28 US disclosed
WO-2022133420-A1 BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF Boehringer Ingelheim Animal Health USA Inc. (US) 2022-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11827657-B2 Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof JAK3, JAK1, JAK2 CA1 2675/4885CA2 1365/4885CA5A 1387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.