Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9931090 | 0.90 | ROCK1 (0.58) | ACACBROCK2RPS6KA5MAP4K4CDK1 | |
| SCHEMBL9931091 | 0.90 | ROCK1 (0.58) | ACACBROCK2RPS6KA5MAP4K4CDK1 | |
| SCHEMBL6947166 | 0.83 | CTSK (0.47) | ALDH1A1KMT2ACYP17A1L3MBTL1MEN1 | |
| SCHEMBL12436366 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1LMNAACACB | |
| SCHEMBL10117995 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1LMNAACACB | |
| SCHEMBL10061707 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KMT2ACYP17A1L3MBTL1MEN1 | |
| SCHEMBL10117998 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1LMNAACACB | |
| SCHEMBL3829625 | 0.81 | KMT2A (0.58) | ALDH1A1KMT2ACYP17A1L3MBTL1MEN1 | |
| SCHEMBL15918786 | 0.79 | ACACB (0.55) | ALDH1A1LMNAACACBTSHRHSD17B10 | |
| SCHEMBL10311694 | 0.79 | KMT2A (0.53) | ALDH1A1KMT2ACYP17A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929672-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2022-08-19 | — | — | CN | disclosed |