Toluene

Toluene

SCHEMBL28844214

Cc1ccccc1.[c]1cccc2nc3ccccc3cc12

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
HPGD P15428 3/20 0.45
GLA P06280 2/20 0.45
ACHE P22303 2/20 0.45
MAPT P10636 1/20 0.45
PDE10A Q9Y233 1/20 0.41
CYP1A2 P05177 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
KDM4E B2RXH2 4/20 0.40
GAA P10253 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
STAT3 P40763 2/20 0.40
KDM1A O60341 2/20 0.39
NQO2 P16083 2/20 0.39
LMNA P02545 2/20 0.39
POLB P06746 1/20 0.39
PTBP1 P26599 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25265 0.89 ALDH1A1 (0.56) ALDH1A1HPGDGLAACHEMAPT
Acridine SCHEMBL28161140 0.80 ALDH1A1 (0.71) ALDH1A1HPGDGLAACHEMAPT
Toluene SCHEMBL28145254 0.77 ALDH1A1 (0.36) ALDH1A1HPGDGLAACHEMAPT
Toluene SCHEMBL28128603 0.76 LMNA (0.48) ALDH1A1HPGDACHECYP1A2KDM4E
SCHEMBL28260376 0.74 KDM4E (0.45) ALDH1A1HPGDGLAACHEMAPT
SCHEMBL18317418 0.70 ALDH1A1 (0.50) ALDH1A1HPGDGLAACHEMAPT
SCHEMBL4106752 0.69 ALDH1A1 (0.48) ALDH1A1HPGDGLAACHEMAPT
SCHEMBL426806 0.69 CYP1A2 (0.50) ALDH1A1CYP1A2RAB9AKDM4EKDM1A
Acridine SCHEMBL27603600 0.69 ALDH1A1 (0.94) ALDH1A1HPGDGLAACHEMAPT
SCHEMBL2700416 0.68 CYP1A2 (0.41) ALDH1A1HPGDGLAMAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106661020-A Heterocyclic compound and organic light emitting element using same 喜星素材株式会社 2017-05-10 CN disclosed