Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31138401 | 0.76 | ALDH1A1 (0.39) | ALDH1A1POLBSMN1; SMN2PLAUKDM4E | |
| SCHEMBL28147259 | 0.76 | ALDH1A1 (0.42) | ALDH1A1POLBSMN1; SMN2PLAUKDM4E | |
| SCHEMBL29237010 | 0.76 | HRH4 (0.38) | POLBSMN1; SMN2PLAUHPGDHTT | |
| SCHEMBL25303426 | 0.73 | DYRK1B (0.41) | ALDH1A1SMN1; SMN2PLAUHTTMAPT | |
| SCHEMBL25799534 | 0.73 | KDM4E (0.39) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL31284617 | 0.72 | ALDH1A1 (0.39) | ALDH1A1POLBSMN1; SMN2PLAUKDM4E | |
| SCHEMBL29837244 | 0.71 | KIF20B (0.39) | ALDH1A1POLBSMN1; SMN2PLAUKDM4E | |
| SCHEMBL23689905 | 0.71 | KIF20B (0.39) | ALDH1A1POLBSMN1; SMN2PLAUKDM4E | |
| SCHEMBL14690650 | 0.70 | NT5E (0.50) | KDM4ELMNA | |
| SCHEMBL22411881 | 0.70 | ALDH1A1 (0.40) | ALDH1A1POLBSMN1; SMN2PLAUKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106810550-A | A kind of preparation method of 7-naphthyridine derivatives | 湖南华腾制药有限公司 | 2017-06-09 | — | — | CN | disclosed |