SCHEMBL29237010

SCHEMBL29237010

Clc1cnc2nc(Cl)cc(Cl)c2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 6/20 0.38
HRH3 Q9Y5N1 2/20 0.38
HTT P42858 3/20 0.37
HSD17B10 Q99714 2/20 0.37
IDO1 P14902 1/20 0.35
POLB P06746 2/20 0.33
LMNA P02545 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
APEX1 P27695 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HPGD P15428 1/20 0.33
PLAU P00749 1/20 0.32
GUSB P08236 3/20 0.32
AURKA O14965 1/20 0.31
KIF11 P52732 1/20 0.31
JAK2 O60674 1/20 0.31
NOS1 P29475 2/20 0.31
DYRK1A Q13627 1/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25303426 0.80 DYRK1B (0.41) HRH4HTTIDO1SMN1; SMN2PLAU
SCHEMBL25799534 0.80 KDM4E (0.39) HTTLMNANOS1
SCHEMBL28844355 0.76 ALDH1A1 (0.42) HTTPOLBLMNASMN1; SMN2HPGD
SCHEMBL3252305 0.71 HTT (0.37) HRH4HRH3HTTHSD17B10IDO1
SCHEMBL31113471 0.71 AXL (0.38) HRH4HRH3HTTHSD17B10IDO1
SCHEMBL247512 0.69 L3MBTL1 (0.52) HTTIDO1LMNASMN1; SMN2HPGD
SCHEMBL29751072 0.68 NOS1 (0.39) HTTHSD17B10LMNACYP2C9TSHR
SCHEMBL28777985 0.68 NOS1 (0.39) HTTHSD17B10LMNACYP2C9TSHR
SCHEMBL14828808 0.68 GUSB (0.36) HRH4HRH3HTTHSD17B10IDO1
SCHEMBL25304094 0.68 GUSB (0.36) HRH4HRH3HTTHSD17B10IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117942786-A Preparation method of nanofiltration membrane and nanofiltration membrane prepared by same 沃顿科技股份有限公司 2024-04-30 CN disclosed