Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684338 | 0.89 | IRAK4 (0.49) | IRAK4MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL29684829 | 0.85 | IRAK4 (0.53) | IRAK4MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL29684405 | 0.83 | IRAK4 (0.55) | IRAK4POLBKMT2AKDM4EHTT | |
| SCHEMBL29732897 | 0.81 | KCNMA1 (0.60) | IRAK4MAPTPOLBSMN1; SMN2NPSR1 | |
| SCHEMBL28844941 | 0.81 | KCNMA1 (0.60) | IRAK4MAPTPOLBSMN1; SMN2NPSR1 | |
| SCHEMBL29684546 | 0.78 | IRAK4 (0.55) | IRAK4POLBKMT2AKDM4EHTT | |
| SCHEMBL29684162 | 0.78 | IRAK4 (0.50) | IRAK4MAPTNPSR1KMT2AKDM4E | |
| SCHEMBL1308558 | 0.78 | F10 (0.55) | MAPTRAB9APOLBSMN1; SMN2NPSR1 | |
| SCHEMBL29732956 | 0.78 | HTT (0.70) | IRAK4RAB9APOLBSMN1; SMN2KMT2A | |
| SCHEMBL28844848 | 0.78 | HTT (0.70) | IRAK4RAB9APOLBSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | claimed |
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | claimed |
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | disclosed |